Our report covers COI across the whole canine genome
Inbreeding is a measure of how closely related your dog’s parents were. The higher the inbreeding coefficient, the more closely related the parents. In general, higher inbreeding coefficients are associated with increased incidence of genetically inherited conditions.
The diversity of the maternal and paternal haplotypes in the Major Histocompatibility Complex (MHC) region of the genome has been found in some studies to be associated with the incidence of certain autoimmune diseases. Dogs that have less diversity in the MHC region haplotypes (i.e. the Dog Leukocyte Antigen (DLA) inherited from the mother is similar to the DLA inherited from the father) are considered less immunologically diverse. A High Diversity result means the dog has two highly dissimilar haplotypes. A Low Diversity result means the dog has two similar, but not identical, haplotypes. A No Diversity result means the dog has inherited identical haplotypes from both parents.
Below is a sample COI for a Golden Retriever in our database.